Name :
Human PLGF-1 Protein, His Tag (MALS verified)
Background :
Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PLGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family – a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PLGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Biological Activity :
Immobilized Human PLGF-1 Protein, His Tag (Cat. No. PGF-H52H5) at 1 μg/mL (100 μL/well) can bind Biotinylated Human VEGF R1, His,Avitag (Cat. No. VE1-H82E3) with a linear range of 1-31 ng/mL (QC tested).
Species :
Source :
Human PLGF-1 Protein, His Tag (PGF-H52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 19 – Arg 149 (Accession # P49763-2 ).
Tag :
Purity :
（Purity）>90% as determined by SDS-PAGE.
Storage and Stability :
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin Level :
（Endotoxin）Less than 1.0 EU per μg by the LAL method.
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Protein Structure :
This protein carries a polyhistidine tag at the C-terminus.
Refactoring Approach :
Please see Certificate of Analysis for specific instructions.
Protein Labeling :
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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